Preparation, Characterization and Photostability Study of Biocomposites Comprising Quantum Dots for Bioimaging Application

Norhidayah Abu; Najihah Ismail; Zuhana Ahmad Zubir; Nik Mohd Azmi Nik Abdul Aziz

doi:10.4028/www.scientific.net/MSF.900.3

Paper Titles

Preparation, Characterization and Photostability Study of Biocomposites Comprising Quantum Dots for Bioimaging Application
p.3

Biodegradable Mg Strengthened Poly-Lactic Acid Composite through Interfacial Properties
p.7

Kenaf Silicone Biocomposites: Synthesis and its Hyperelastic Behaviour
p.12

Fabrication and Microstructure Evaluation of Fibrous Composite for Acetabular Labrum Implant
p.17

Biocomposites Formulated with Virgin/Recycled Acrylonitrile Butadiene Styrene
p.23

Synthesis of Multi-Walled Carbon Nanotube-Zirconia Composite and Bovine Serum Albumin Adsorption Characteristics
p.27

Preparation of Polymer Nanoparticles and Application on Nitrile-Butadiene Rubber Reinforcement
p.35

Synthesis and Pore Structure Characterisation of Novel Mesoporous MgO-CeO₂/SBA-15 as a Potential Catalyst Support
p.40

HomeMaterials Science ForumMaterials Science Forum Vol. 900Preparation, Characterization and Photostability...

Preparation, Characterization and Photostability Study of Biocomposites Comprising Quantum Dots for Bioimaging Application

Abstract:

Cadmium based quantum dots (Cd QDs) is well established and extensively used for various applications, but found limiting usage in bioimaging application, due to its high toxicity and insolubility in aqueous solution. Passivation and/or encapsulation of the Cd QDs with a non-toxic and biocompatible polymer are common practice to overcome the drawback. In our work, CdSe is synthesized as a core and encapsulated with ZnS to produce a hydrophobic colloidal core/shell CdSe/ZnS QD. Then, a biocompatible PEGylated amphiphilic polymer as matrices is used to encapsulate CdSe/ZnS QD for converting it into water dispersible property which required for in-vitro imaging applications. The cell viability and cellular uptake of the biocomposite were studied against cancerous and non-cancerous cells. Also, peak of emission spectrum was recorded to determine the photostability of this biocomposites under continuous UV light illumination up to 100 minutes.

You might also be interested in these eBooks

Research and Application of Functional Materials

View Preview

Info:

Periodical:

Materials Science Forum (Volume 900)

Pages:

3-6

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.900.3

Citation:

Cite this paper

Online since:

July 2017

Authors:

Norhidayah Abu*, Najihah Ismail, Zuhana Ahmad Zubir, Nik Mohd Azmi Nik Abdul Aziz

Keywords:

Bioimaging, Cell Viability, Fluorescence, Photostability, Quantum Dot

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] R. Bakalova, Z. Zhelev, D. Kokuryo, L. Spasov, I. Aoki and T. Saga: International Journal of Nanomedicine Vol. 6 (2011), pp.1719-1732.

Google Scholar

[2] K. Yong, Y. Wang, I. Roy, H. Rui, M. T. Swihart, W. Law, S. K. Kwak, L. Ye, J. Liu, S. D. Mahajan and J. L. Reynolds: Theranostics Vol. 2 (2012), pp.681-694.

DOI: 10.7150/thno.3692

Google Scholar

[3] B. R. Liu, J. G. Winiarz, J. Moon, S. Lo, Y. Huang, R. S. Aronstam and H. Lee: Colloids and Surfaces B: Biointerfaces Vol. 11 (2013), pp.162-170.

Google Scholar

[4] Y. Su, Y. He, H. Lu, L. Sai, Q. Li, W. Li, L. Wang, P. Shen, Q. Huang and C. Fan: Biomaterials Vol. 30 (2009), pp.19-25.

Google Scholar

[5] I. L. Medintz, H. T. Uyeda, E. R. Goldman and H. Mattoussi: Nature Materials Vol. 4 (2005), pp.435-4.

Google Scholar