Development of Mesoporous Magnetic Hydroxyapatite Nanocrystals

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Mesoporous magnetic hydroxyapatite nanocrystals (MPmHAp NCs) were successfully prepared through one-step co-precipitate process. From the results, the MPmHAp NCs kept HAp lattice structure and had short rod-like morphology with superparamagnetic property. The size of MPmHAp was 60-80 nm in length and 10-20 nm in width. It also had excellent cell viability when coculture with 3T3 cells in vitro. In addition, MPmHAp NCs not only possessed mesoporous architecture with high surface area for effective drug loading capacity and drug release. The above results indicate that the biocompatible MPmHAp NCs showed great potential as multifunctional therapeutic nanoagent for biomedical application.

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161-165

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March 2018

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© 2018 Trans Tech Publications Ltd. All Rights Reserved

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