Selection of Polyanions as Complexation Agent in the Formation of Nanochitosan by Polyelectrolyte Complex Method

Abstract:

The aqueous dispersion of nanochitosan was prepared by polyelectrolyte complex (PEC) method with various mixing ratios of chitosan and polyanions, i.e., chitosan-glucomannan, chitosan-hyaluronic acid, and chitosan-Arabic gum. The formation of nanochitosan was carried out by adding the polyanion solution dropwise into the acid solution of chitosan. The study aimed to determine the best polyanion among the variations tested in this study, concerning the targeted particle size and the stability of the dispersion over time. Particle size distribution was observed by Particle Size Analyzer (PSA). The result indicated that Arabic gum gave the smallest average particle size, i.e. 192.5 nm, at a chitosan/polyanion mass ratio of 3:1 and pH value of 4.

• Periodical: Materials Science Forum (Volume 948)
• Pages: 140-145
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.948.140
• Online since: March 2019
• Authors: Al Dina N. Khoerunisa, Prihati Sih Nugraheni, Mohammad Fahrurrozi, Wiratni Budhijanto*
• Keywords: Arabic Gum, Chitosan, Glucomannan, Hyaluronic Acid, Polyelectrolyte Complex

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