Effect of Boiled Water Parasite Kapok (Dendrophthoe pentandra) Leaves on Total Cholesterol Levels and Histopathology of Hepar of Hypercholesterolemic Mice

Andi Mu'nisa; Yusminah Hala; A. Mushawwir Taiyeb; Dwi Kesuma Sari

doi:10.4028/www.scientific.net/MSF.967.51

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Effect of Boiled Water Parasite Kapok (Dendrophthoe pentandra) Leaves on Total Cholesterol Levels and Histopathology of Hepar of Hypercholesterolemic Mice
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HomeMaterials Science ForumMaterials Science Forum Vol. 967Effect of Boiled Water Parasite Kapok...

Effect of Boiled Water Parasite Kapok (Dendrophthoe pentandra) Leaves on Total Cholesterol Levels and Histopathology of Hepar of Hypercholesterolemic Mice

Abstract:

This study aims to determine effect of boiled water parasite kapok (Dendrophthoe pentandra) leaves on the total cholesterol level and histopathology of hepar of hypercholesterolemic mice (mus musculus). This study used 20 ICR male mice divided into 4 treatment groups namely normal mice group, hypercholesterolemic mice group, mice group with boiled water kapok parasite at a dose of 400 mg/kg BW, and 800 mg/kg BW, respectivelly. The animal group was given boiled water kapok parasite after standard feeding and cholesterol feed for 2 weeks. The parameters observed in this study were total cholesterol levels, the amount of fat granules in the liver tissue of mice which were observed in the form of liver-preserved preparations made by paraffin method. The results showed that the administration of parasitic kapok (Dendrophthoe pentandra) at a dose of 400 mg/kg BW and 800 mg/kg BW had an effect on decreasing the total cholesterol level of mice and the histopathology of hepar of showed improvement after the therapy.

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Periodical:

Materials Science Forum (Volume 967)

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51-55

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.967.51

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Online since:

August 2019

Authors:

Andi Mu'nisa*, Yusminah Hala, A. Mushawwir Taiyeb, Dwi Kesuma Sari

Keywords:

Dendrophthoe Pentandra Leaves, Histopathology of Hepar, Hypercholesterolemia, Total Cholesterol

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References

[1] Tajoda, H.N., J.C. Kurian., and M.B. Bredenkamp., Reduction of Cholesterol and Triglycerides in Volunteer using Lemon and Apple, International Journal of Humanities and Social Science., 2013,Vol. 3,No. 18.

Google Scholar

[2] Valkenburg, JLCH. Dendrophthoe pentandra (L.) Miq. In RHMJ Lemmens and N Bunyapraphatsara (Eds.) Plant Resources of South East Asia (PROSEA) 12, Medicinal and Poisonous Plants., 2003, (pp.159-158). Bogor, Indonesia: Prosea Foundation.

DOI: 10.1021/np068237h

Google Scholar

[3] Huaxing, Q, Hua-hsing, C, Hua-xing, K & Gilbert, MG. 2003. Loranthaceae. Flora of China5: 220-239.

Google Scholar

[4] Kirana, C., R. Mastuti, M.A. Widodo, S.B. Sumitro, S. Indriyani, dan B. Alfi. 2001. Komposisi Bahan Bioaktif Benalu. Jurnal Ilmu-Ilmu Teknik (Engineering)., 2001, Vol. 13 (2); 193-204.

Google Scholar

[5] Rufaida, Fanny, Aulanni'am & Sri Murwani. 2006. Profil Kadar Kolesterol Total, Low Density Lipoprotein (LDL) Dan Gambaran Histopatologis Aorta Pada Tikus (Rattus Norvegicus) Hiperkolesterolemia Dengan Terapi Ekstrak Air Benalu Mangga (Dendropthoe Pentandra). Program Studi Pendidikan Dokter Hewan Universitas Brawijaya.

DOI: 10.31001/biomedika.v12i2.637

Google Scholar

[6] Artanti N, T Firmansyah and A Darmawan. 2012. Bioactivities Evaluation of Indonesian Mistletoes (Dendrophthoe pentandra L.) Miq.) Leaves Extracts. Journal of Applied Pharmaceutical Science., 2012 Vol. 02 (01):24-27.

Google Scholar

[7] Riesanti,D.G, Masdiana, Herawati. 2008. Kadar HDL, Kadar LDL, dan Gambaran Histopatologi Aorta Pada Hewan Model Tikus (Rattus norvegicus) Hiperkolesterolemia dengan Terapi Ekstrak Air Benalu Mangga (Dendrophthoe pentandra). Program Studi Kedokteran Hewan. Universitas Brawijaya. Malang.

DOI: 10.21776/ub.vetbioclinj.2019.001.01.1

Google Scholar

[8] Nurjanah, LI. dan A. Asadatun., Antioxidant activity dan bioactive compound of Solenspp, Ilmu Kelautan, 2011, 16 (3) 119-124.

Google Scholar

[9] Ramadani, P.R, Aulanni'am, Herawati. 2013. Potensi Ekstrak Air Benalu Mangga (Dendrophtoe petandra) Terhadap Aktivitas Enzim Lipoprotein Lipase (LPL) Serum Dan Histopatologi Duodenum Hewan Model Tikus (Rattus norvegicus) Hiperkolesterolemia. Program Studi Pendidikan Dokter Hewan, Universitas Brawijaya. Vol 2 (3).

DOI: 10.21776/ub.vetbioclinj.2019.001.01.1

Google Scholar

[10] Singh, R., S. Kumar., A.C. Rana., and N. Sharma., Different Models of Hepatotoxicity and Related Hepar Diseases. IRJP, 2012, 3 (7).

Google Scholar