Cerium Oxide Nanoparticles Protect Primary Embryonic Mouse Fibroblasts from Oxidative Stress Induced by Low-Temperature Argon Plasma Treatment

Abstract:

Cerium oxide (CeO₂) nanoparticles are regarded as one of the most promising materials for biomedical applications. Due to their antioxidant activity CeO₂ nanoparticles are capable of protecting cells from oxidative stress induced by various physical or chemical factors. In this paper we have investigated the protective effect of CeO₂ nanoparticles in the model of oxidative stress induced by low-temperature argon plasma, which is characterized by multiply damaging factors, including different types of radiation (ultraviolet and infrared), free radicals and reactive oxygen species. It was shown that citrate-stabilized cerium oxide nanoparticles protect primary embryonic mouse fibroblasts from the action of plasma, maintaining a high level of cell viability.

• Periodical: Nano Hybrids and Composites (Volume 13)
• Pages: 294-300
• DOI: https://doi.org/10.4028/www.scientific.net/NHC.13.294
• Online since: January 2017
• Authors: Nelli R. Popova, Artem M. Ermakov, Anton L. Popov, Irina I. Selezneva, Azamat Y. Akkizov, Olga S. Ivanova, Vladimir K. Ivanov
• Keywords: Cerium Oxide Nanoparticles, Low-Temperature Argon Plasma, Oxidative Stress

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