Comparative Study of MgFe₂O₄ and ZnFe₂O₄ Nanoparticles Synthesized by Different Methods for Use in Magnetic Bioactive Glass for Hyperthermia Treatment

Abstract:

Although magnetic nanoparticles have been widely studied, limited research has compared different ferrite types and synthesis routes for use in hyperthermia-based bioactive glass applications. This study aims to synthesize magnetic materials from two types of ferrites: magnesium ferrite (MgFe₂O₄) and zinc ferrite (ZnFe₂O₄). These ferrite nanoparticles were synthesized using two distinct methods; the conventional solid-state reaction and the co-precipitation method in order to identify the optimal synthesis route and the most suitable type of magnetic material for hyperthermia treatment. The data demonstrated that MgFe₂O₄ powder with synthesis by using the solid-state method consistently presented higher value of magnetic properties compared to those synthesized by co-precipitation method under higher calcination temperature. Moreover, ZnFe₂O₄ powder was found to be unsuitable for use as a precursor in hyperthermia treatment because of its structure typically leads to antiferromagnetic or superparamagnetic behavior. The effect of MgFe₂O₄ containing in bioactive glass was investigated. The oxide precursors of bioactive glass were mixed with varying amounts of MgFe₂O₄ and subsequently melted to form glass at 1400 °C. The phase formation presented SiO₂ was the dominant phase and coexisted with Na₂CO₃, MgSiO₃, Fe₃O₄, Na₂Ca (PO₄)₂SiO₄, Ca₂SiO₄, and Na₄Ca₄Si₆O₁₈. However, the MgFe₂O₄ phase was not observed in all of glass-ceramic samples. This may be due to MgFe₂O₄ decomposed during the high-temperature melting process at 1400 °C. Nevertheless, these magnetic bioactive glass ceramic samples exhibited magnetic properties, which were attributed primarily to the presence of Fe₃O₄.

• Periodical: Nano Hybrids and Composites (Volume 51)
• Pages: 1-6
• DOI: https://doi.org/10.4028/p-3fmAmU
• Online since: May 2026
• Authors: Thanaporn Boonchoo, Pannapat Promkrajang, Chonlathit Pitipoomsuksan, Wilaiwan Leenakul*
• Keywords: Co-Precipitation, Magnetic Properties, MgFe₂O₄, Soft Magnetic, Solid-State Reaction

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