Green Synthesis of Azadirachta Indica- Based Silver Nanoparticles for Antimicrobial Orthodontic Applications

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This study investigates the green synthesis of silver nanoparticles (AgNPs) using Azadirachta indica extract and their incorporation onto orthodontic brackets, enhanced with different concentrations of Azadirachta indica extract. AgNPs exhibit strong antimicrobial activity, making them promising agents in biomedical applications. The synthesized AgNPs were characterized using UV-Vis spectroscopy, FTIR, XRD, and FESEM. The AgNPs were embedded into orthodontic brackets to assess their antimicrobial properties against Staphylococcus aureus and Escherichia coli. Characterization results confirmed the successful formation of crystalline, spherical AgNPs with sizes ranging from 30–68 nm. Antimicrobial testing revealed clear zones of inhibition around AgNP-coated brackets, demonstrating enhanced antibacterial efficacy. The study supports the potential of eco-friendly synthesized AgNPs for improved oral health in orthodontic treatments.

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7-12

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May 2026

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© 2026 Trans Tech Publications Ltd. All Rights Reserved

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[1] M. A. Al-Mutairi, L. Al-Salamah, L. A. Nouri, B. S. Al-Marshedy, N. H. Al-Harbi, E. A. Al-Harabi, H. A. Al-Dosere, F. S. Tashkandi, Z. M. Al-Shabib, A. M. Altalhi. Microbial Changes in the Periodontal Environment Due to Orthodontic Appliances: A Review. 16(7). (2024) pp.5-12.

DOI: 10.7759/cureus.64396

Google Scholar

[2] S. K. Mallineni, S. Sakhamuri, S. L. Kotha, A. R. G. M. AlAsmari, G. H AlJefri, F. N. Almotawah, S. Mallineni, & R. Sajja. Silver nanoparticles in dental applications: A Descriptive review. Bioengineering, 10(3), 327. (2023).

DOI: 10.3390/bioengineering10030327

Google Scholar

[3] M. A. Alzohairy. Therapeutics Role ofAzadirachta indica(Neem) and Their Active Constituents in Diseases Prevention and Treatment. Evidence-based Complementary and Alternative Medicine (2016) pp.1-11.

DOI: 10.1155/2016/7382506

Google Scholar

[4] B. Barik, B. S. Satapathy, G. Pattnaik, D. V. Bhavrao & K. P. Shetty. Sustainable synthesis of silver nanoparticles from Azadirachta indica: antimicrobial, antioxidant and in silico analysis for periodontal treatment. Frontiers in Chemistry. (2024) pp.1-14.

DOI: 10.3389/fchem.2024.1489253

Google Scholar

[5] Jaisankar, Applications of silver nanoparticles in dentistry. International Journal of Research in Pharmaceutical Sciences, (2020) p.1126–1131.

Google Scholar

[6] S. Ahmed. Green Synthesis of Silver Nanoparticles Using Azadirachta Indica Aqueous Leaf Extract. Vol 9 (1). 2025 pp.1-7.

Google Scholar

[7] M. S. N. Salleh, R. R. Ali., K. Shameli, M. Y. Hamzah, R. Kasmani & M. M. Nasef. Interaction Insight of Pullulan-Mediated Gamma-Irradiated Silver Nanoparticle Synthesis and Its Antibacterial Activity. Polymers, 13(20), (2021) p.354.

DOI: 10.3390/polym13203578

Google Scholar