The billet of magnesium AZ31B was made by twin-screw rheo-cast, and the specimen cut from the rheo-cast billet and normal cast billet were compressed in Gleeble-3000 hot simulator. The deformation temperature was 300, 350, and the strain rates were 0.001~1s-1. The relationship among flow stress, deformation temperature and strain rates were analyzed. The variation of the microstructure was observed and compared after the specimen was hot compressed. The results show that the surface of the rheo-cast specimen is much more smooth than the normal cast specimen after the compression. The dynamic recrystallization had taken place during the compression and the recrystallized grain of rheo-cast sample is more tiny than normal cast specimen.