Fabricating Nanofluidic Channels and Applying them for DNA Molecules Study

Abstract:

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In the emerging field of nanobiotechnology, further downsizing the fluidic channels and pores to the nanometer scale are attractive for both fundamental studies and technical applications. The insulation Silicon nitride membrane nanofluidic channel arrays which have width ~50nm and depth ~80nm and length ≥20μm were created by focused-ion-beam instrument. The λ-DNA molecules were put inside nanochannels and transferred, a fluorescence microscopy was used to observe the images. Only by capillary force, λ-DNA molecules moved inside the nanochannels which dealt with activating reagent Brij aqueous solution. These scope nanostructure devices will help us study DNA transporting through a nanopore and understand more DNA dynamics characteristics.

Info:

Periodical:

Solid State Phenomena (Volumes 121-123)

Edited by:

Chunli BAI, Sishen XIE, Xing ZHU

Pages:

777-780

DOI:

10.4028/www.scientific.net/SSP.121-123.777

Citation:

K. G. Wang et al., "Fabricating Nanofluidic Channels and Applying them for DNA Molecules Study", Solid State Phenomena, Vols. 121-123, pp. 777-780, 2007

Online since:

March 2007

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Price:

$35.00

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