Preparation and Properties of Nanocomposite of Poly(L-Lactide) and Surface Grafted Hydroxyapatite

Abstract:

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nanocomposites of poly (L-lactide) (PLLA) and hydroxyapatite (HAP) or surface grafted hydroxyapatite (g-HAP) were prepared by ultrafines hot-pressing method, and the properties were investigated by polarized optical microscopy (POM), scanning electron microscopy (SEM), mechanical test and cell culture. Results showed that the PLLA segment grafted onto the HAP surface played a positive role on improving the interfacial compatibility between the g-HAP and the PLLA matrix. Compared with the HAP/PLLA composites, the bending strength and bending modulus of the g-HAP/PLLA composites were obviously enhanced, which was proportional to the nHAP:nL-LA ratio. The result of POM showed that the g-HAP particles acted as an effective heterogeneous nucleating agent in the g-HAP/PLLA composite. Fibroblasts culture indicated that the g-HAP/PLLA composites had better cytocompatibility than PLLA and HAP/PLLA composites. Hence, g-HAP/PLLA composites will be a promising material for bone tissue engineering.

Info:

Periodical:

Edited by:

Barry Tan

Pages:

238-243

DOI:

10.4028/www.scientific.net/AMM.108.238

Citation:

B. H. Luo et al., "Preparation and Properties of Nanocomposite of Poly(L-Lactide) and Surface Grafted Hydroxyapatite", Applied Mechanics and Materials, Vol. 108, pp. 238-243, 2012

Online since:

October 2011

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Price:

$35.00

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