Hydraulic disc brake is essential for meeting the requirements of safety and economic efficiency during drilling and work-over procedure. To address this need, we have developed a programmable logic controller controlled novel hydraulic disc brake system with capability to apply control strategy similar to anti-lock braking system for hoisting system of truck-mounted drilling rig. This paper is to investigate the complicated interaction between the work clamp and the hydraulic control system. So designers can use this model to decide which control strategies are more suitable for the disc brake. This is demonstrated by modeling the advanced hydraulic system and simulating influential factors on dynamic characteristics of hoisting system disc brake, with the application of the Advanced Modeling Environment for Simulations of Engineering Systems. The method of modeling and simulation provides a simple, effective approach to studying hydraulic disc brake for hoisting system.