The friction and wear behaviors of PTFE composites filled with irregular or spherical copper powders were experimentally investigated. The effects of shape, content and size of the copper powders on the tribological properties of the PTFE composites were discussed. The results showed that the friction coefficients of the PTFE composites filled with irregular copper powders are higher than that of pure PTFE. While the friction coefficients of the PTFE composites filled with spherical copper powders were almost always lower than that of pure PTFE. Both irregular and spherical copper powders can effectively decrease the wear of the composites. The wear of the composites filled with spherical copper powders will gradually decrease with the increase of the content of copper. But the effect of the content of irregular copper powder on the wear of the composites was not so obvious. The friction coefficients and wear depths of the composites increase with the decrease of the Cu size. The increase amplitudes in friction coefficients and wear depths of the spherical Cu filled composites are smaller than those of the irregular Cu filled composites.