Synthesis of Juglone and its Derivatives

Abstract:

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Juglone (1), plumbagin (2) and isoplumbagin (3) were synthesized from the natural product 4,8-dihydroxy naphthol-β-D-glucoside (4) which existed large amount in barks of Juglans mandshurica. Juglone was achieved directly by deglycosylation catalyzing with CAS in 78 % yield. Plumbagin was synthesized by five steps with an overall yield of 22 %. Isoplumbagin was synthesized by six steps in 24 % yield.

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Periodical:

Edited by:

Honghua Tan

Pages:

1139-1141

DOI:

10.4028/www.scientific.net/AMM.138-139.1139

Citation:

J. L. Wang et al., "Synthesis of Juglone and its Derivatives", Applied Mechanics and Materials, Vols. 138-139, pp. 1139-1141, 2012

Online since:

November 2011

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$35.00

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