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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 138-139Production of a Fibrinolytic Enzyme from Coprinus...

Production of a Fibrinolytic Enzyme from Coprinus comatus YY-20

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Abstract:

A strong fibrin-specific fibrinolytic enzyme was produced by liquid culture of Coprinus comatus YY-20. Soybean cake powder and sucrose as substrates resulted in the highest fibrinolytic activity. The optimal temperature for the production of the enzyme was found to be 21-25°C in the optimal medium (Soybean cake powder 50 g/L, sucrose 20 g/L). The optimal initial pH of the medium was found to be at the range of 5-8. The maximum fibrinolytic activity was observed at the stationary phase of cell growth. These results suggest that the culture liquid of Coprinus comatus YY-20 has potential as a source of physiologically active fibrinolytic enzymes.

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Applied Mechanics and Mechanical Engineering II

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Periodical:

Applied Mechanics and Materials (Volumes 138-139)

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1195-1201

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https://doi.org/10.4028/www.scientific.net/AMM.138-139.1195

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Online since:

November 2011

Authors:

Xiao Lan Liu, Xi Qun Zheng, Juan Kun Zhang

Keywords:

Coprinus comatus, Fermentation, Fibrinolytic Enzyme, Liquid Culture

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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