In recent years, the bio-oil, as a new kind of clean energy, has been paid with more attentions and has been in rapid development. Meanwhile, the design and research of the bio-oil equipment also has made a great progress. This paper presented the research of the main unit installed steel structure which was with the 3000t yearly capacity. It analyzed and researched the structure and load characteristics of the bio-oil main unit installed steel structure. According to the related research theory and design standards, by using software ANSYS establish the three-dimensional model of the main unit installed steel structure. The paper also analyzed and calculated the wind load. The model structure has been optimized on the foundation of the analyzing preliminary model foundation. The stability of the equipment has been enhanced.