A New Loading Device Driven by Voice Coil Motor

Article Preview

Abstract:

The mechanical environment has an important influence on biological behavior of the human musculoskeletal system. Either in vivo or in vitro culture, the growth and development of the musculoskeletal tissue depend on the mechanical environment. Now we propose a new loading device which uses a voice coil motor as driving force to further optimize tissue engineering bioreactor. It can not only provide tissue engineering in vitro culture with different sizes and frequency of loading environments within the physiological range, but also detect the mechanical properties of the culture in building process. This device, which uses the voice coil motor as driving force and closed-loop encoder to control displacement, has the characteristics of low power loss, high acceleration and smooth loading, and can achieve a high-precision loading process with different ranges such as from high-speed to low-speed. The device can facilitate the load research in build process of the engineered musculoskeletal system.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

250-253

Citation:

Online since:

September 2013

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2013 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] Chunqiu Zhang, Mingli Sun, Jing Li, Jinzhuo Ye, Haiying Liu. Advances of mechanical conditions in engineering cartilage tissue [J]. Journal of Medical Biomechanics, Vo. l24 , No. 6, Dec. (2009).

Google Scholar

[2] Wolchok JC, Brokopp C, Underwood CJ, et al. The effect of bioreactor induced vibrational stimulation on extracellular matrix production from human derived fibroblasts. Biomaterials. 2009; 30(3): 327-335.

DOI: 10.1016/j.biomaterials.2008.08.035

Google Scholar

[3] Concaro S, Gustavson F, Gatenholm P. Bioreactors for tissue engineering of cartilage. Adv Biochem Eng Biotechnol. 2009; 112: 125-143.

Google Scholar

[4] Schulz RM, Bader A. Cartilage tissue engineering and bioreactor systems for the cultivation and stimulation of chondrocytes. Eur Biophys J. 2007; 36(4-5): 539-568.

DOI: 10.1007/s00249-007-0139-1

Google Scholar

[5] Laganà K, Moretti M, Dubini G, et al. A new bioreactor for the controlled application of complex mechanical stimuli for cartilage tissue engineering. Proc Inst Mech Eng H. 2008; 222(5): 705-715.

DOI: 10.1243/09544119jeim383

Google Scholar

[6] Jun Liao, Liping Du. The door assembly structure natural frequency and vibration form of modal analysis. MC Now parts. 2008; 7; 95-97.

Google Scholar