A Layered Model for the Growth of Solid Tumors in Vascular Phase

Abstract:

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We divide a solid tumor in vascular phase into a vascular layer, an oxygen-diffusion layer, an oxygen-resistant layer and a necrotic layer outside-to-inside, and have constructed a layered model for tumor growth. The actual growth curves of the tumors have been obtained by using different invasion speeds of the vascular layer. The simulative calculation results indicate that the angiogenesis rate is positively correlated with malignant degree of the tumors, if the tumors enter vascular phase, survival time of tumor patients is about 1-4 years, but the tumor patients without angiogenesis can live with tumor.

Info:

Periodical:

Edited by:

Long Chen, Yongkang Zhang, Aixing Feng, Zhenying Xu, Boquan Li and Han Shen

Pages:

736-739

DOI:

10.4028/www.scientific.net/AMM.43.736

Citation:

K. H. Zhan et al., "A Layered Model for the Growth of Solid Tumors in Vascular Phase", Applied Mechanics and Materials, Vol. 43, pp. 736-739, 2011

Online since:

December 2010

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Price:

$35.00

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