Influence of Acute Incremental Exercise on Antioxidation-Endocrine-Immune Network of PM2.5 Exposed Rats

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The paper is to study the mechanism of antioxidation-endocrine-immune network through exercise with rice after PM2.5 been exposed. The 40 male Wistar SPF rats were randomly divided into the QC, EC, LPE, MPE, HPE. the serum GSTs, T-AOC, GSH-Px, NE, T, C, FT, TNF-α, IL-1β were tested.The results showed that the activity of GST, C, NE, IL-1β have upward trend but the T-AOC, GSH-Px and T declined compared with the QC; compared with the EC group, all PM2.5 exposed+exerxise have the same upward oe downward trend compared with EC. Conclusion: PM2.5 exposure can destroy the antioxidant and immune defence, it has dose-response ralationships with the PM2.5 doses concentration; the negtive influence of PM2.5 to antioxidation-endocrine-immune network may be one of the mechanism of sports ability decline in the air pollution environment.

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805-808

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January 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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