Efficient Synthesis of O-glycosyl-5′-H-Phosphonate Diesters of d4T

Guo Dong Liu; Shan Shan Gong; Si Liu; Qi Sun

doi:10.4028/www.scientific.net/AMM.483.92

Paper Titles

Investigation on Work Hardening Effect Generated during Dynamic Formation of Al-Based Coating on Magnesium Alloy
p.75

Synthesis of d4T- 5′-glycosyl-1″-phosphoramidates from H-Phosphonates via an Oxidative Coupling Strategy
p.79

A Brief Review of Cardanol-Based Surfactants
p.83

A Novel H-Phosphonate Method for the Synthesis of D-Mannose-1-Phosphate
p.88

Efficient Synthesis of O-glycosyl-5′-H-Phosphonate Diesters of d4T
p.92

Synthesis of 4-Hydroxyl Pyrazolo[3,4-d]pyrimidines from the Corresponding 4-Chloride Precusors with Acetic Acid
p.96

Preparation of Magnetic Nanoparticles from Byproduct of Titanium Dioxide-Copperas
p.100

Research on and Applications of Au/Pt Thermocouples
p.105

Effect of Near β Heat Treatment Process on Microstructure of TC18 Alloy
p.110

HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 483Efficient Synthesis of O-glycosyl-5′-H-Phosphonate...

Efficient Synthesis of O-glycosyl-5′-H-Phosphonate Diesters of d4T

Abstract:

A novel and one-pot route for the synthesis of O-glycosyl-5′-H-phosphonate diesters of d4T has been developed. This analogs were synthesized by controlling tandem substitution reaction on PCl₃ with 2,6-lutidine as suitable base.

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Applied Mechanics and Materials (Volume 483)

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92-95

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https://doi.org/10.4028/www.scientific.net/AMM.483.92

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December 2013

Authors:

Guo Dong Liu, Shan Shan Gong, Si Liu, Qi Sun*

Keywords:

Antiviral Nucleoside, d4T, H-Phosphonate Diester, Phosphorus Trichloride, Prodrug

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