Synthesis of 4-Hydroxyl Pyrazolo[3,4-d]pyrimidines from the Corresponding 4-Chloride Precusors with Acetic Acid

Jian Sun; Shan Shan Gong; Qi Sun

doi:10.4028/www.scientific.net/AMM.483.96

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Efficient Synthesis of O-glycosyl-5′-H-Phosphonate Diesters of d4T
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Synthesis of 4-Hydroxyl Pyrazolo[3,4-d]pyrimidines from the Corresponding 4-Chloride Precusors with Acetic Acid
p.96

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 483Synthesis of 4-Hydroxyl Pyrazolo[3,4-d]pyrimidines...

Synthesis of 4-Hydroxyl Pyrazolo[3,4-d]pyrimidines from the Corresponding 4-Chloride Precusors with Acetic Acid

Abstract:

A novel and efficient method for the synthesis of 4-hydroxy-6-substituted-pyrazolo [3,4-d] primidines with acetic acid via phenol esters intermediate has been developed. Compared to the results obtained from the base substituted conditions, acetic acid catalyzed synthesis afforded target products in good yields.

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Applied Mechanics and Materials (Volume 483)

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96-99

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https://doi.org/10.4028/www.scientific.net/AMM.483.96

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December 2013

Authors:

Jian Sun, Shan Shan Gong, Qi Sun*

Keywords:

Acetic Acid, Ester, Hydrolysis, Pyrazolo[3,4-d]pyrimidine, Substitution

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