Identifying Protein Structural Classes by a Fusion Sequence Encoding Scheme

Abstract:

Article Preview

In this study, a novel sequence encoding scheme is introduced by fusing PseAA and PSSM. However, this sequence encoding scheme would correspond to a very high dimensional feature vector. A dimensionality reduction algorithm, the so-called NPE (Neighborhood Preserving Embedding) is introduced to extract the key features from the high-dimensional space. Finally, the K-NN (K-Nearest Neighbor) classifier is employed to identify the types of protein structures. Our jackknife test results thus obtained are quite encouraging, which indicate that the above methods are used effectively to deal with this complicated problem of predicting protein structural classes.

Info:

Periodical:

Edited by:

Qi Luo

Pages:

843-847

DOI:

10.4028/www.scientific.net/AMM.58-60.843

Citation:

T. Wang et al., "Identifying Protein Structural Classes by a Fusion Sequence Encoding Scheme", Applied Mechanics and Materials, Vols. 58-60, pp. 843-847, 2011

Online since:

June 2011

Export:

Price:

$35.00

In order to see related information, you need to Login.

In order to see related information, you need to Login.