Qumai Total Flavonoids Induced Diabetic Mice Model of Streptozotocin

Ming San Miao; Bo Lin Cheng; Na Jiang; Mei Qiong Jiang

doi:10.4028/www.scientific.net/AMM.664.410

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 664Qumai Total Flavonoids Induced Diabetic Mice Model...

Qumai Total Flavonoids Induced Diabetic Mice Model of Streptozotocin

Abstract:

Purpose: Research Qumai total flavonoids induced diabetic mice model of streptozotocin. Methods: 12 h after fasting groups of mice, Tail vein injection of citrate buffer chain urea with cephalosporins solution (80mg/kg,0.02ml/10g), To 1 times a day. In dosing 10, 20, 30 days tail blood glucose measurement value. On the 30th day fasting 12 h after the last for 1 h, Some blood, Measuring blood glucose、Glycosylation of serum protein, Serum insulin、Insulin resistance value;After the death in mice,Take the liver glycogen original value;Take the pancreas, and kidneys,10% formalin fixed liquid, As a pathological. Results: Compared with model group、blank group, each dose of dianthus superbus flavonoids to chain urea with cephalosporins cause diabetes in mice model can significantly improve the experiment indexes. Conclusion: Dianthus superbus flavonoids to chain urea with cephalosporins caused diabetes in mice model has good therapeutic effect.

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Periodical:

Applied Mechanics and Materials (Volume 664)

Pages:

410-414

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.664.410

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Online since:

October 2014

Authors:

Ming San Miao*, Bo Lin Cheng, Na Jiang, Mei Qiong Jiang

Keywords:

Metformin Hydrochloride Tablets, Qumai Total Flavonoids, Streptozotocin

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* - Corresponding Author

References

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