Synthesis and Characterization of Photocurable Biodegradable Elastomers

Abstract:

The aim of this study was to synthesize a serious of biodegradable elastomers by photocurable reaction as a potential biomaterial for the delivery of protein drugs. The macromonomers was prepared via ring opening reaction at 140°C later methacrylic acylated at 50°C. The optimal conditions were investigated and the property of the two macromonomer precursors were characterized via GPC and 1H-NMR. The cross-link degree of the elastomers can be adjusted by changing the concentration of photoinitiator (DMPA), furthermore influence the elastomers’ degradation rate. it could provide more appropriate choice for the elastomers in application.

• Periodical: Applied Mechanics and Materials (Volume 665)
• Pages: 359-362
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.665.359
• Online since: October 2014
• Authors: Fang Yuan Guo, Xia Shen, Xiao Hong Pei, Gen Sheng Yang*
• Keywords: Elastomer, Ring-Opening, UV Cross-Link

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