Electrospinning of Poly(Lactic Acid)/Poly(Lactic Acid-Co-Lysine) Blend

Abstract:

Electrospun poly (lactic acid)/poly (lactic acid-co-lysine) (PLA/PLL) blend were prepared, and the structures including fibers, beads and microspheres and properties of electrospun material were characterized. Viscosity, conductivity and surface tension of electrospinning solution had critical effect on the structures of the electrospun blend. The optimization process conditions of PLA/PLL electrospun fibers, beads and microspheres were confirmed and the structures, thermal properties, crystal properties, and hydrophilicity were analyzed. The results showed that the average diameter of electrospun PLA/PLL fibers was less than that of PLA under the same spinning process, and the crystallinity of spun products was affected by solution concentration, pushing speed and spinning voltage. Accurate controlling of spinning product morphology can be achieved by adjusting the formulation of electrospinning solution and spinning process. The addition of PLL into PLA could improve the hydrophilicity of electrospun PLA/PLL products.

• Periodical: Applied Mechanics and Materials (Volume 665)
• Pages: 371-374
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.665.371
• Online since: October 2014
• Authors: Jun Yan Yao*, Yu Jie Li, Zhi Du, Ming He Chen
• Keywords: Blend, Electrospinning, Morpholoy, Poly (lactic acid-co-lysine), Poly(lactic acid) (PLA)

References

[1] A. C. Vega-Lugo, L. T. Lim. Effects of Poly(ethylene oxide) and pH on the Electrospinning of Whey Protein Isolate[J]. Polymer Science, 2012, 50(16): 1188-1197.

DOI: 10.1002/polb.23106

[2] L. J. Valle, R. Camps, A. Díaz, et al. Electrospinning of polylactide and polycaprolactone mixtures for preparation of materials with tunable drug release properties[J]. Polymer Research, 2011, 18: 1903-(1917).

DOI: 10.1007/s10965-011-9597-3

[3] E. D. Boland, G. E. Wnek, D. G. Simpson, et al. Tailoring tissue engineering Scaffolds using electroprocessing techniques: A study of poly(glycolic acid) electrospinning[J]. Macromolecular Science, 2001. 38(12): 123l-1243.

DOI: 10.1081/ma-100108380

[4] K. Kim, M. Yu, X. Zong, et al. Control of degradation rate and hydrophilicity in electrospun non-woven poly(D, L-lactide) nanofiber scaffolds for biomedical applications[J]. Biomaterials, 2003, 24(27): 4977-4986.

DOI: 10.1016/s0142-9612(03)00407-1

[5] G. Pitarresi, F. S. Palumbo, C. Fiorica, et al. Electrospinning of α, β-poly(N-2-hydroxyethyl)- DL-aspartamide graft-polylactic acid to produce a fibrillar scaffold[J]. European Polymer Journal, 2010, 46: 181-184.

DOI: 10.1016/j.eurpolymj.2009.09.001

[6] P. Agarwal, P. K. Mishra, P. Srivastava. Statistical optimization of the electrospinning process for chitosan/polylactide nanofabrication using response surface methodology[J]. Material Science, 2012, 47: 4262-4269.

DOI: 10.1007/s10853-012-6276-7

[7] Y. Kong, J. Yuan, Z. Wang, et al. Study on the Preparation and Properties of Aligned Carbon Nanotubes/Polylactide Composite Fibers[J]. Polymer Composites, 2012, 33: 1613-1619.

DOI: 10.1002/pc.22298

[8] H. Yu, X. Shen, Y. Li, et al. Design, synthesis and characterization of a novel cationic polymer poly(lactic acid-b-l-lysine)[J]. Macromolecular Science, 2010, 47(3): 230-234.

DOI: 10.1080/10601320903526949