Fabrication of NF-PLLA Scaffolds by Gel Extraction Phase Separation

Zhi Hang He; Jia Liu; Guo Jie Xu; Jian Jin Jiao; Xiu Feng Xiao

doi:10.4028/www.scientific.net/AMR.1033-1034.1090

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 1033-1034Fabrication of NF-PLLA Scaffolds by Gel Extraction...

Fabrication of NF-PLLA Scaffolds by Gel Extraction Phase Separation

Abstract:

The 1, 4-dioxane/ethanol mixed solvent was used as solvent system, and the gel extraction phase separation method was adopted to prepare porous PLLA nanofibrous scaffolds. At that, we studied the effect of using different gel temperature to influence nanofibrous PLLA scaffolds’ structure and performance. The results showed that the morphology of nanofibers and the diameter of fibers could be regulated by gel temperature; a lower gel temperature resulted in higher crystallinity of PLLA scaffold. In addition, the PLLA scaffolds have excellent interconnected network when the gel temperature was in the range of-20 to-10°C. The PLLA scaffolds will become a material to repair the bone tissue, hopefully.