Synthesis of the Key Intermediate of (+)-(6S,2'R)-Cryptocaryalactone

Article Preview

Abstract:

A concise route to total synthesis of (+) - (6S, 2'R)-cryptocaryalactone (1) was designed and the key intermediate (7) was synthesized. The route included an Evans Aldol reaction, TBS protection and DIBAL-H reduction.

You might also be interested in these eBooks

Info:

Periodical:

Advanced Materials Research (Volumes 1033-1034)

Pages:

566-568

Citation:

Online since:

October 2014

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] L. A. Collett, M. T. Davies-Coleman, D. E. A. Rivett, Prog. Chem. Org. Nat. Prod. 1998, 75, 181; I. Collins, J. Chem. Soc., Perkin Trans. 1 1999, 1377.

Google Scholar

[2] M. Kalesse, M. Christmann, U. Bhatt, M. Quitschalle, E. Claus, A. Saeed, A. Burzlaff, C. Kasper,L. O. Haustedt, E. Hofer, T. Scheper, W. Beil, ChemBio Chem 2001, 2, 709; M. Kalesse, M. Christmann, Synthesis 2002, 981; L. Bialy, H. Waldmann, Chem. Commun. 2003, 1872; S. B. Buck, C. Hardouin, S. Ichikawa, D. R. Soenen, C. -M. Gauss, I. Hwang, M. R. Swingle, K. M. Bonness, R. E. Honk -anen , D. L. Boger, J. Am. Chem. Soc. 2003, 125, 15694.

DOI: 10.1002/1439-7633(20010903)2:9<709::aid-cbic709>3.0.co;2-7

Google Scholar

[3] T. R. Govindachari, P. C. Parthasarathy, J. D. Modi, Ind. J. Chem. 1972, 10, 149; G.F. Spencer, R. E. England, R. B. Wolf, Phytochemistry 1984, 23, 2499; S. E. Drewes, M. M. Horn, R. S. Shaw, Phytochemistry 1995, 40, 321; H. H. Meyer, Liebigs Ann. Chem. 1984, 977; Y. Mori, H. Furukawa, Chem. Pharm. Bull. 1994, 42, 2161.

Google Scholar