Effect of Curcumin on Diabetes in an Alloxan Mice Model

Ming San Miao; Shuo Tian; Lin Guo

doi:10.4028/www.scientific.net/AMR.1051.363

Paper Titles

Physiological and Biochemical Responses of Miscanthus sacchariflorus to Salt Stress
p.333

Bacillus pumilus to Disrupt the Quorum Sensing Reduce the Mortality of Gibel Carp (Carassius auratus gibelio) Caused by Aeromonas hydrophila
p.341

Formation of THMs, Microcystin-LR and Odors from Microcystis aeruginosa - Derived Organic Matter
p.348

In Vitro Cytotoxic Studies of Ultrafine TiO₂/Graphene Oxide Sheet Nanocomposites in Human Alveolar Epithelial Cells
p.353

Effect of Curcumin on Diabetes in an Alloxan Mice Model
p.363

Physiological and Biochemical Changes of Cherry Rootstocks under Salt Stresses in Greenhouse Environment
p.368

Research of the Unknown Cause of Death of Caesio diagramma
p.373

The Effects of Quality Changes in Pomfret (Pampus argenteus) Fillets from Different Treatments during Chilled Storage
p.378

Effects of Nano-Selenium on Kindey Selenium Contents, Glutathione Peroxidase Activities and GPx-1 mRNA Expression in Mice
p.383

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1051Effect of Curcumin on Diabetes in an Alloxan Mice...

Effect of Curcumin on Diabetes in an Alloxan Mice Model

Abstract:

Objective: Research on the effect of Curcumin on diabetes in an alloxan mice model. Methods: The positive control group was given Diamicron suspension; High, medium and low treatment groups were given different doses of curcumin solution; Blank group and model group are given the same volume of saline. When the tenth, twentieth, thirtieth day of the administration, measured the blood glucose (BG) of the mice, after the last administration, observed pathological changes of the pancreas under light microscope. Results: Compared with normal control group, the model group level of BG were significantly higher in 10 days,20days,30days and the emergence of pancreatic lesions. Curcumin treatment groups were significantly reduced these abnormalities (P<0.05,P<0.01).Conclusion:Curcumin can reduce the lever of BG at the early diabetic mice and improved the pancreatic lesions caused by diabetes.

You might also be interested in these eBooks

Applied Engineering Decisions in the Context of Sustainable Development

View Preview

Info:

Periodical:

Advanced Materials Research (Volume 1051)

Pages:

363-367

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1051.363

Citation:

Cite this paper

Online since:

October 2014

Authors:

Ming San Miao*, Shuo Tian, Lin Guo

Keywords:

Blood Glucose, Curcumin Diabetic Mellitus

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] SY Fang, MH Xu, HX Gu, et al, Effects of Radix Pueraria Flavonoids in Da Bie Shan Zone on Blood Glucose and Lipid Level of Diabetic Mice Induced by Alloxan, J. Journal of West An hui University. 28(2012)7-9.

Google Scholar

[2] Q Li, J Jin, Y Xu, The pharmacological effect of curcumin and its clinical application,J. Modern Journal of Integrated Traditional Chinese and Western Medicine. 21(2012)1366-1368.

Google Scholar

[3] J Zheng, H Chen, The pharmacological effects and clinical application of curcumin, J. Strait Pharmaceutical Journal. 23(2011)84-87.

Google Scholar

[4] LL Shao, YY Dai, WH Feng, The Progress of Curcumin in Metabolic Syndrome, J. Progress in Modern Biomedicine. 13(2013)3988-3992.

Google Scholar

[5] RH Guo, HL Wang, YM Zhai, et al, Effects of soybean trypsin inhibitor on glucose tolerance and hepatic glycogen in alloxandiabetic mice, J. Journal of Clinical Rehabilitative Tissue Engineering Research. 15(2011)4477-4480.

Google Scholar

[6] ZZ Lin, T Chen, The study of Gypenosides hypoglycemic effect in experimental diabetic mice, J. Longyan University. 29(2011): 51-53.

Google Scholar