Effect of Curcumin on the Level of Blood Lipid and Blood Glucose in Diabetic Rat Model

Ming San Miao; Lin Guo; Shuo Tian; Tan Wang

doi:10.4028/www.scientific.net/AMR.1051.419

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1051Effect of Curcumin on the Level of Blood Lipid and...

Effect of Curcumin on the Level of Blood Lipid and Blood Glucose in Diabetic Rat Model

Abstract:

Objective: To investigate the effects of curcumin on blood lipid and blood glucose levels and its mechanism in diabetic rat model. Method: After streptozotocin (STZ) induced diabetic rat model, large, medium and small doses of curcumin group were partly given curcumin solution 400,200,100mg·kg^-1, administered once a day, continuously 30 days. In 30 th day, determine blood glucose (BG) value, after the last injection , determine the serum total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) levels. Results: Compared with the model group rats, each dose of curcumin group rats’ BG, TC, TG and LDL-C levels were significantly decreased, HDL-C levels was increased significantly. Conclusion: Curcumin has a certain impact on blood lipids and blood glucose in diabetic rat model.

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Periodical:

Advanced Materials Research (Volume 1051)

Pages:

419-422

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1051.419

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Online since:

October 2014

Authors:

Ming San Miao*, Lin Guo, Shuo Tian, Tan Wang

Keywords:

Blood Glucose, Blood Lipid, Curcumin, Diabetes

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