The Influence of Additives on Hydroxyapatite Biological Coatings of Titanium Alloy Substrate

Abstract:

In this paper, the biological coatings were studied by adding different kinds of additives (TiO₂, Al₂O₃ and ZnO) to hydroxyapatite (HA). The different mass ratio of additives and HA in suspension was mixed with n-butyl alcohol as solvent, triethanolamine as dispersant. The HA composite coatings with additives on titanium alloy substrate were prepared by the method of electrophoretic deposition (EPD). The coatings were characterized by scanning electron microscopy (SEM), Ca/P atomic ratio in composite coatings was analyzed by Energy Dispersive Spectrometer (EDS). The results showed that surface of HA coatings was more uniform and dense by adding TiO₂ than Al₂O₃ or ZnO; and when adding the same kind of additive, the content was higher, there were more holes in HA coatings and surface of the coatings was less uniform. When HA was 15 g/L and TiO₂ was 5 g/L in suspension, Ca/P atomic ratio was 1.56, that’s the most close to the body's natural bone (~ 1.61). HA coatings can be implanted in the body after a short time of ossification and exhibited a good bioactivity.

• Periodical: Advanced Materials Research (Volume 1053)
• Pages: 461-465
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1053.461
• Online since: October 2014
• Authors: Sheng Jiang Wu, Hui Ping Shao, Tao Lin, Zi Fen Zhao
• Keywords: Additives, Bioactivity, Electrophoretic Deposition (EPD), HA, Suspension

References

[1] Wang Z C, Ni Y J, Huang J C. Effects of suspension power content on the electrophoretic deposition of hydroxyapatite coatings[J]. Journal of the Chinese Ceramic Society, 2008, 36（5）: 626-630.

[2] Chen F, Lin C J, Wang Z C. The electrophoretic deposition of nano hydroxyapatite coating on titanium surface. Electrochemistry, 2005, 11（1）: 67-70.

[3] Uchida M, Oyane A, Kim H M, et al. Biomimetic Coating of Laminin–Apatite Composite on Titanium Metal and Its Excellent Cell-Adhesive Properties [J]. Advanced Materials, 2004, 16(13): 1071-1074.

DOI: 10.1002/adma.200400152

[4] Yang D H, Shao H P, Fan L P, et al. Porosity and mechanical properties of porous Ti-7. 5Mo alloy for medical applications by gelcasting [J]. Journal of University of Science and Techno logy Beijing, 2011, 33（9）: 1122-1126.

[5] Boon Sing Ng, Ingegerd Annergren, Andrew M Soutar, et al. Characterization of a duplex TiO2/CaP coating on Ti6Al4V for hard tissue replacement [J]. Biomaterials, 2005, 26: 1087-1095.

DOI: 10.1016/j.biomaterials.2004.04.022

[6] Wei R. The preparation and property research of bioactive coating on the surface of porous implant material [M]. Beijing: University of Science and Techno logy Beijing, (2012).

[7] Yao L. Study of hydroxyapatite coatings on pure titanium substrate by electrophoretic deposition method [D]. Shandong: Shandong University, (2007).

[8] Geng Z, Electrochemical Preparation and Characterization of the HAP/Ag Composite Coating [D]. Fujian: Xiamen University, (2008).

[9] Han H J, Yun H, Ye Q. The Preparation of HA/ZrO2 Composite Coatings by Electrophoretic Deposition Method [C]. The 13th National Conference on Electrochemistry, (2005).

[10] Pattanayak D, Kawai T, Matsushita T, et al. Effect of HCl concentrations on apatite-forming ability of NaOH–HCl and heat-treated titanium metal [J]. Journal of Materials Science: Materials in Medicine, 2009, 20(12): 2401-2411.

DOI: 10.1007/s10856-009-3815-0

[11] Gemelli E, Resende C, de Almeida Soares G. Nucleation and growth of octacalcium phosphate on treated titanium by immersion in a simplified simulated body fluid [J]. Journal of Materials Science: Materials in Medicine, 2010, 21(7): 2035-(2047).

DOI: 10.1007/s10856-010-4074-9

[12] Wen H B, Liu Q, De Wijn J R, et al. Preparation of bioactive microporous titanium surface by a new two-step chemical treatment [J]. Journal of Materials Science: Materials in Medicine, 1998, 9(3): 121-128.