The implementation and application of manufacturing execution system (MES) is an important way to improve the management level and realize information management for automobile parts manufacturing enterprises. System selection is the basis and prerequisite for MES implementation. Analytic hierarchy process (AHP) is applied in MES system selection in this paper based on the analysis of the MES system selection decision-making problem for automobile parts manufacturing enterprises. Firstly, the MES system selection decision indicators are established from the aspects of system technology performance, system suitability, quality of services and input-output of the MES system. On the basis, three solutions for MES system is analyzed and evaluated by AHP approach. The study of this paper provided a feasible solution for MES system selection decision-making.