To achieve success in the marketplace, human factors play an important role in product development. In this paper a design strategy considering anthropometric variability for different demographic data was put forward. With the aid of parametric technology of Computed Aided Design (CAD), concept model of products was initialized. Detailed parameters of products were configured according to the anthropometric information based on measurement of customers’. Multiple linear regression were used to model the relation between the product comfort and design variables, thus the sizes of products could adapt to specific customers of certain age, height and gender. A children’s scooter was demonstrated as a case to validate this strategy. A three dimension parametric model of a scooter was built first, the parameters concerned with human factors were determined according to the knowledge of anthropometry.