Use of SPECT with 99mTc-Pyrophosphate Combined with a Perfusion Myocardium Scintigraphy in the Evaluation of Inflammatory Changes of the Heart in Patients with Persistent Atrial Fibrillation

Svetlana I. Sazonova; Yuri B. Lishmanov; Julia N. Ilyushenkova; Roman E. Batalov; Julia V. Rogovskaya

doi:10.4028/www.scientific.net/AMR.1084.523

Paper Titles

Use of ^99mTc-HMPAO in Evaluating the Results of Cerebral Hypoperfusion Prevention in the Patients with Coronary Heart Disease after Coronary Artery Bypass Grafting
p.506

Use of Autoleukocyte, Labelled with ^99mTc-Exametazine for Evaluation of Inflammatory Changes in Myocardium
p.511

Use of Pulse Oximetry in Radiotherapy
p.515

Use of Single Photon Emission Computed Tomography (SPECT) with ^99mTc-MIBI for Evaluation of Neoadjuvant Chemotherapy Effectiveness of Larynx and Laryngopharynx Cancer Treatment
p.519

Use of SPECT with ^99mTc-Pyrophosphate Combined with a Perfusion Myocardium Scintigraphy in the Evaluation of Inflammatory Changes of the Heart in Patients with Persistent Atrial Fibrillation
p.523

Use of Technetium-99m-Labeled Lipophilic Complex of Methoxy-Isobutyl-Isonitrile and Iopromide Radiopaque Substance to Assess the Severity of Coronary Atherosclerosis in Patients with Coronary Heart Disease at Mild Disorders of Myocardial Perfusion
p.527

Use of Technetium-99m-Labeled Methoxy-Isobutyl Isonitrile and Iodine 123-Labeled Phenyl-Methyl-Pentadecanoic Acid in the Diagnosis and Prognosis of Patients with Dilated Cardiomyopathy
p.532

Use of Technetium-99m-Labelled Sodium Diphosphate Decahydrate to Assess Right Ventricle Dysfunction in Patients with Pulmonary Embolism
p.536

Using Nanotech Radiopharmaceutical for the Visualization of Sentinel Lymph Nodes in Patients with Cervical Cancer
p.540

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1084Use of SPECT with 99mTc-Pyrophosphate Combined...

Use of SPECT with ^99mTc-Pyrophosphate Combined with a Perfusion Myocardium Scintigraphy in the Evaluation of Inflammatory Changes of the Heart in Patients with Persistent Atrial Fibrillation

Abstract:

The purpose was to study the utility of technetium 99m - pyrophosphate in the diagnoses of inflammatory changes of the heart in patients with persistent atrial fibrillation. The study included 30 patients (20 men and 10 women, mean age is 46 ± 9.92 years) with idiopathic persistent atrial fibrillation. To identify the foci of inflammatory changes in the myocardium the scintigraphy with ^99mTc-Pyrphotech and myocardial perfusion scintigraphy with ^99mTc-methoxy-isobutyl-isonitrile (99mTc-MIBI) was performed before the operation. Later, both scintigrams were combined. During the surgical intervention, in all patients an endomyocardial sampling for histological and immunohistochemical study was performed. Pathological accumulation of ^99mTc-Pyrphotech in the myocardium was detected in 8 (26%) of examined patients. In 20% of cases the cause of "idiopathic" form of AF is latent lymphocytic or polymorphocellular myocarditis of viral etiology. Scintigraphy with ^99mTc-Pyrphotech can serve as one of the primary methods for non-invasive diagnosis of myocardial inflammation at the given form of arrhythmia.

You might also be interested in these eBooks

Radiation and Nuclear Techniques in Material Science

View Preview

Info:

Periodical:

Advanced Materials Research (Volume 1084)

Pages:

523-526

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1084.523

Citation:

Cite this paper

Online since:

January 2015

Authors:

Svetlana I. Sazonova, Yuri B. Lishmanov, Julia N. Ilyushenkova, Roman E. Batalov, Julia V. Rogovskaya

Keywords:

^99mTc-Methoxyisobutyl Isonitrile, ^99mTc-Pyrophosphate, Atrial Fibrillation, Myocarditis

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] W.B. Kannel, P.A. Wolf, E.J. Benjamin, Levy D. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates, Am. J. Cardiol. 16 (1998) 2-9.

DOI: 10.1016/s0002-9149(98)00583-9

Google Scholar

[2] O.D. Pedersen, P. Søndergaard, T. Nielsen, S.J. Nielsen, E.S. Nielsen, N. Falstie-Jensen, I. Nielsen, L. Køber, H. Burchardt, M. Seibaek, C. Torp-Pedersen. Atrial fibrillation, ischaemic heart disease, and the risk of death in patients with heart failure, Eur Heart J. 27 (2006).

DOI: 10.1093/eurheartj/ehl359

Google Scholar

[3] P.A. Wolf, R.D. Abbott, W.B. Kannel . Atrial fibrillation as an independent risk factor for stroke: the Framingham Study, Stroke. 22 (1991) 983-988.

DOI: 10.1161/01.str.22.8.983

Google Scholar

[4] S. Stewart. Atrial fibrillation in the 21st century: the new cardiac Cinderella" and new horizons for cardiovascular nursing, Eur J Card. Nurs. 1 (2002) 115-121.

DOI: 10.1016/s1474-5151(02)00010-5

Google Scholar

[5] D. Li, S. Fareh, T.K. Leung, S. Nattel. Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort, Circulation. 6 (1999) 87-95.

DOI: 10.1161/01.cir.100.1.87

Google Scholar

[6] A.M. Peters, H.J. Danpure, S. Osman, R.J. Hawker, B.L. Henderson, H.J. Hodgson, J.D. Kelly, R.D. Neirinckx, J.P. Lavender. Clinical experience with 99m Tc-hexamethylpropylene-amineoxime for labelling leucocytes and imaging inflammation, Lancet. 25 (1986).

DOI: 10.1016/s0140-6736(86)90601-x

Google Scholar

[7] T Strecker , J Rösch , M Weyand , A Agaimy . Endomyocardial biopsy for monitoring heart transplant patients: 11-years-experience at a german heart center, Int J Clin Exp Pathol. 6 (2013) 55-65.

Google Scholar