Using Nanotech Radiopharmaceutical for the Visualization of Sentinel Lymph Nodes in Patients with Cervical Cancer

Abstract:

The study of radionuclide determination of SLN and optimization of surgical treatment in organ-sparing treatment of invasive cervical cancer included 26 patients with cervical cancer of stage I. To identify sentinel lymph nodes a nanocolloid was administered one day prior to the planned operation. Sentinel lymph nodes were identified in 26 patients. A comparative evaluation of the sensitivity of techniques for determining SLN, depending on the method, has showed that the SPECT sensitivity was 72%, with radiometry this indicator was 93.3%. The technique of intraoperative radiometric determination of SLN is more efficient in comparison with SPECT. The optimum is the combined use of both techniques, when the probability of SLN detection increases to 91.4%.

• Periodical: Advanced Materials Research (Volume 1084)
• Pages: 540-544
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1084.540
• Online since: January 2015
• Authors: Ivan Sinilkin, Vladimir Chernov, Alena Chernishova, Larisa Kolomiets, Anna Titskaya, Roman Zelchan*
• Keywords: Cervical Cancer, Nanotech Radiopharmaceutical, Sentinel Lymph Node, Trachelectomy

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