Using Nanotech Radiopharmaceutical for the Visualization of Sentinel Lymph Nodes in Patients with Larynx and Hypopharynx Cancer

Abstract:

The study included 17 patients. All patients with cancer of larynx and hypopharynx were injected with nanocolloid labeled with 99mTc. In total 22 lymph nodes are identified. In the study of distant sentinel lymph nodes the presence of metastatic disease was revealed in 2 patients (11.8%). In 15 patients (88.2%) there was no metastatic lesion of SLN, and nodal disease progression was not recorded during further observation. Thus, in our study we did not observe the phenomenon of the so-called "jumping" metastases. Single-photon emission computed tomography and intraoperative radiometric display allow determining the “sentinel” lymph nodes after subserous administration of radioactive colloid with a sensitivity of 100% and a specificity of 100%.

• Periodical: Advanced Materials Research (Volume 1084)
• Pages: 545-548
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1084.545
• Online since: January 2015
• Authors: Ivan Sinilkin, Vladimir Chernov, Evgeny T. Choynzonov, Svetlana Chijevskaya, Anna Titskaya, Roman Zelchan*
• Keywords: Cancer of Larynx, Hypopharynx Cancer, Nanotech Radiopharmaceutical, Sentinel Lymph Node

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