Synthesis and Photophysical Property of Polyion Complex Micelle Incorporating Phthalocyanine Zinc(II) Bearing Benzyl Ether Dendritic Substituents with Nitro-Terminal Group

Abstract:

A new phthalocyanine Zinc(II) bearing benzyl ether dendritic substituents with nitro-terminal group: tetra-{3,5-[di-(4-nitro benzyloxy) benzyloxy]} Phthalocyanine Zinc(II) (ZnPc(NO2)8), was synthesis and characterized by IR, 1HNMR, MALDI-TOF-MS and UV/Vis. UV/Vis spectra of ZnPc(NO2)8 exhibited characteristic absorption peaks at 290, 350 and 680 nm, and fluorescence emission peak was at 692 nm with a quantum yield at 0.20 in dimethylsulfoxide (DMSO). The polymeric nanoparticle ZnPc(NO2)8@MPEG-PLGA was formed between the amphiphilic block copolymer poly(ethylene glycol)-polylactic and polyglyctic acids (PEG-PLGA) and ZnPc(NO2)8, ZnPc(NO2)8@MPEG-PLGA formed a core-shell-type nanoparticle with diameter about 70 nm. UV/Vis spectra and fluorescence emission spectra of ZnPc(NO2)8@MPEG-PLGA were obviously lower than that of free ZnPc(NO2)8 in buffer solution, and with varying degrees of redshift. ZnPc(NO2)8@MPEG-PLGA would be a promising third-generation photosensitizer for PDT.

• Periodical: Advanced Materials Research (Volume 1088)
• Pages: 495-499
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1088.495
• Online since: February 2015
• Authors: Xiao Dong Zhu, Zhen Zhen Chen, Ke Qin Wu, Jun Ri Wen, Xiong Wei Wang, Yi Ru Peng*
• Keywords: Dendritic Phthalocyanine, Phthalocyanines Zinc(II), Polymeric Micelles

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