Poly(Vinyl Alcohol)/Chitosan Nanofibrous Membrane Containing Anredera cordifolia (Ten.) Steenis

Abstract:

A novel nanofibrous membrane that has potential application as antimicrobial wound dressing has been developed. The membrane consisted of PVA and chitosan as a matrix and extract of Binahong leaves as an active antibacterial material for wound dressing. In this study, ex situ fabrication of nanofibrous membrane composed of poly(vinyl alcohol)/chitosan/extract of binahong leaves were described. The fibers were electrospun from a precursor solution composed of 10 ml of PVA 14 %w/v, 2 ml of chitosan 2 % w/v and 4 ml of extract of binahong leaves 2.5% w/v. Nanofibrous membrane yielded from this method was characterized by Scanning Electron Microscopy (SEM), and X-Ray Diffraction (XRD). SEM result showed that morphology and diameter of nanofibers were affected by applied voltage and flowrate. Through X-RD it was found that the addition of binahong leaves extract decreased the crystallinity of the electrospun PVA/chitosan nanofibrous membrane.

• Periodical: Advanced Materials Research (Volume 1112)
• Pages: 453-457
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1112.453
• Online since: July 2015
• Authors: Ade Yeti Nuryantini, Muhammad Miftahul Munir, Annisa Rahma, Tri Suciati, Khairurrijal Khairurrijal
• Keywords: Binahong, Chitosan, Nanofibrous Membrane, Poly(vinyl alcohol), Wound Dressing

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