Synthesis and Characterization of Thiol- and Carboxyl-Functionalized Mesoporous Silica Nanoparticles

Wan Xia Wang; Yu Wang; Hua Meng Gong; Hong Hao Sun; Ming Xing Liu

doi:10.4028/www.scientific.net/AMR.1142.220

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1142Synthesis and Characterization of Thiol- and...

Synthesis and Characterization of Thiol- and Carboxyl-Functionalized Mesoporous Silica Nanoparticles

Abstract:

The purpose of this article is to synthesize the thiol-and carboxyl-bifunctionalized mesoporous silica nanoparticles (CMS-SH-COOH). CMS-SH-COOH was successfully synthesized by co-condensation and post-grafting methods. Moreover, the particle size and structural properties of CMS-SH-COOH were characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS) and Fourier transform infrared spectroscopy (FT-IR). The obtained results indicated that the CMS-SH-COOH presented a uniform spherical shape with a wormhole arrangement of the mesopores and a relatively narrow paticle distribition. Therefore, the CMS-SH-COOH might be a great potential carrier for the drug delivery system in the future.

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2016 International Conference on Advanced Material Research and Application

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Periodical:

Advanced Materials Research (Volume 1142)

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220-224

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1142.220

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Online since:

January 2017

Authors:

Wan Xia Wang, Yu Wang, Hua Meng Gong, Hong Hao Sun, Ming Xing Liu*

Keywords:

Carboxyl Group, Functionalization, Mesoporous Silica Nanoparticles, Thiol Group

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