The Effect of Visible Light-Activated TiO₂ Thin Film on Nosocomial Pathogens

Abstract:

Many methods had been developed to disinfect or sterilize the medical equipment or hospital environment for controlling the spread of nosocomial pathogens. This study was aimed to evaluate the effect of titanium dioxide (TiO2) thin film on preventing nosocomial infection. Firstly, TiO2 thin film was prepared by using the modified impregnation method and further analysis by field-emission scanning electron micrographs and X-ray diffractometer. The nano-size and Anatase crystal structure were confirmed. By using visible light activation of TiO2 thin film for 30 min, the inhibition of Enterococcus faecalis, Streptococcus bovis, Streptococcus agalactiae, and Staphylococcus aureus by TiO2 thin film treatment were 27.4%, 73.3%, 56.6%, and 9.4%, respectively. In addition, several important Gram negative bacteria causing nosocomial infection were also investigated. The inhibition rate of Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli were 32.5%, 31.3%, and 22.4%, respectively. The results revealed that TiO2 thin film activated by visible light may be useful for decreasing nosocomial infection.

• Periodical: Advanced Materials Research (Volumes 123-125)
• Pages: 268-271
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.123-125.268
• Online since: August 2010
• Authors: Chen Yu Chang, Shih Kuang Hsu, Chen Jung Chang, Yaw Nan Shieh, Ching Lan Chang, Hsueh Hsia Lo
• Keywords: Impregnation Method, Nosocomial Pathogen, TiO₂ Thin Films, Visible Light

References

[1] Y.Y. Chen, F.D. Wang, C.Y. Liu and P. Chou: Infect. Control. Hosp. Epidemiol. Vol. 30 (2009), p.39.

[2] S.H. Maa, H.L. Lee, Y.C. Huang, J.H. Wu, T.S. Tsou, K. MacDonald and I. Abraham: Infect. Control. Hosp. Epidemiol. Vol. 29 (2008), p.767.

[3] G. McDonnell and A.D. Russell: Clin. Microbiol. Rev. Vol. 12 (1999), p.147.

[4] L.S. David and W.A. Anders: Environ. Sci. Technol. Vol. 25(1991), p.777.

[5] B. Kim, D. Kim, D. Cho and S. Cho: Chemosphere Vol. 52 (2003), p.277.

[6] J.M.C. Robertson, P.K.J. Robertson and L.A. Lawton: J. Photochem. Photobiol. A: Chem. Vol. 175 (2005), p.51.

[7] T.C. Cheng, C.Y. Chang, C.I. Chang, C.J. Hwang, H.C. Hsu, D.Y. Wang and K.S. Yao: Surf. Coat. Technol. Vol. 201 (2008), p.925.

[8] K.S. Yao, D.Y. Wang, W.Y. Ho, J.J. Yan and K.C. Tzeng: Surf. Coat. Technol. Vol. 201 (2007), p.6886.

[9] C. Maneerat and Y. Hayata: Int. J. Food Microbiol. Vol. 107 (2006), p.99.

[10] L.F. Liu, J. Barford, K.L. Yeung and G. Si: J. Environ. Sci. China Vol. 19 (2007), p.745.