The Inhibition Effect of TiO2/Ag Thin Film on Acinetobacter baumannii
The nosocomial infections caused by opportunistic pathogen Acinetobacter baumannii was increasing in recent years. It was known that the attachment of A. baumannii on solid surface was a key factor for infection. This study was conducted to evaluate the inhibitory effect of titanium dioxide (TiO2)/Ag thin film on A. baumannii. In this study, TiO2 thin films were firstly prepared by using the modified impregnation method, then TiO2/Ag thin films were prepared by using the spin-coating with 5000 ppm Ag+. The TiO2/Ag thin film was analyzed by field-emission scanning electron micrographs and X-ray diffractometer. The nano-size and Anatase crystal structure were confirmed. Twenty clinical A. baumannii isolates were examined for the bactericidal effect of TiO2/Ag thin film either in the dark or under visible light activation for 20 min. The inhibition efficiencies of TiO2/Ag thin film under visible light on these 20 isolates ranged from 41% to 90%. The effects of TiO2/Ag thin film in the dark were slightly lower than visible light-activated group. Our results suggested that coating of TiO2/Ag on solid surface in hospital environment might be helpful for the prevention of nosocomial A. baumannii infection.
Joong Hee Lee
L. L. Hsieh et al., "The Inhibition Effect of TiO2/Ag Thin Film on Acinetobacter baumannii", Advanced Materials Research, Vols. 123-125, pp. 272-275, 2010