In this paper, the effect of viscous damper on seismic performance of steel-concrete hybrid structure for high-rise building is analyzed. The result shows that viscous damper has little effect on dynamic properties of structure. The story lateral displacement, story drift rotation and damage of structure can be reduced effectively by viscous damper. The effect of the viscous damper on structure seismic performance is better with the increase of seismic intensity. Under the 7, 8 and 9 degree seismic seldom intensity, the story lateral displacement of the top floor decreases at 17.2%, 23.3%, 33.4% and the story drift rotation decreases at 20.8%, 27.2%, 44.7% respectively. The seismic analysis result may be referred by designer and researcher.