Determination of DNJ of Mulberry Latex and Evaluation of the Hypoglycemic Effect on Mice

He Yu Zhang; Wei Chen; Tai Chu Wang; Jin Zhu Liu

doi:10.4028/www.scientific.net/AMR.175-176.36

Paper Titles

Cloning and Expression Analysis of Acetylcholinesterase Gene (Bm-ace1, Bm-ace2) from Domesticated Silkworm, Bombyx mori
p.13

Transcriptional Expression of Serpin-6 Gene in Bombyx Mori Larval after Infection of Bacteria at Different Developmental Stages
p.19

Separation and Identification of Proteins Related to Fruits Ripening in Mulberry (Morus alba)
p.25

Differential Expression Analysis of Fat Body Proteome during Pupation in Silkworm (Bombyx mori)
p.30

Determination of DNJ of Mulberry Latex and Evaluation of the Hypoglycemic Effect on Mice
p.36

Studies on the Joint Impact of Mulberry Cultivation and Sericulture Enterprise as a Scheme for Border Area Development Programme in Kashmir, India
p.41

Cloning and Transcriptional Expression of CYP6AE22-A Member of Cytochrome P450 Family from Bombyx mandarina
p.46

Full Length cDNA Cloning and Expression Characteristics of Ace Gene from Wild Silkworm, Bombyx mandarina
p.51

Expression Profiles of Glutathione S-Transferase Genes in Bombyx mori Exposed to NaF
p.56

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 175-176Determination of DNJ of Mulberry Latex and...

Determination of DNJ of Mulberry Latex and Evaluation of the Hypoglycemic Effect on Mice

Abstract:

Mulberry trees (Morus spp. Moraceae) are used for rearing the silkworm. Moraceae plants are characterized by the presence of latex, and mulberry trees exude latex when their stem, leaf or root were damaged. We found in the present study that mulberry latex contains very high concentrations of DNJ (0.63% wet weight, 4.5% dry weight), the DNJ content of latex varied with different part of tree and collecting time. The study also evaluated the antihyperglycemic effects of mulberry latex on streptozotocin induced diabetic mice. Diabetic mice were treated with mulberry latex or acarbose with food for 21 days. The results indicated that postprandial blood glucose and fasting-blood glucose level of mice were lowed, mulberry latex displayed a significant reduction ( P ≤ 0.05) in blood glucose. This finding suggested that mulberry latex have high value for herbal medicine as hypoglycemic function.

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Advanced Materials Research (Volumes 175-176)

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36-40

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https://doi.org/10.4028/www.scientific.net/AMR.175-176.36

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Online since:

January 2011

Authors:

He Yu Zhang, Wei Chen, Tai Chu Wang, Jin Zhu Liu

Keywords:

Latex, Mulberry, α-Glucosidase Inhibition

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References

[1] B. L. Karina Lucas, T. Marcela and A. A. Aristéa: Botany Vol. 87 (2) (2009), p.202

Google Scholar

[2] A. Anurag Agrawal, K. Kotaro Latex: Annual Review of Ecology, Evolution, and Systematics Vol. 40 (2009), p.311

Google Scholar

[3] K. Kotaro, O. Hiroshi, N. Masatoshi, K. Tateishi and C. Hirayama: Proc Natal Acad Sci U S A. Vol. 103 (5) (2006), p.1337

Google Scholar

[4] L. Monnier, C. Colette , C. Cauble and A. Avignon: Diabetes Care Vol. 25 (2002), p.737

Google Scholar

[5] T. Kimura, K. Nakagawa and H. Kubota: Journal Agriculture Food Chemistry Vol. 55, (14) ( 2007), p.5869

Google Scholar

[6] N. Wasano, K. Konno , M. Nakamura, C. Hirayama, M. Hattori and K. Tateishi: Phytochemistry Vol. 70 (4) (2009), p.880

DOI: 10.1016/j.phytochem.2009.04.014

Google Scholar

[7] W.Q. Liu, X. R. Zhu: Bulletin of Sericulture Vol.37 (4) (2006), p.31

Google Scholar

[8] J. M. Park, H. Y. Bong and H. I. Jeong: Nutrition Research and Practice Vol. 3 (4) (2009), p.272

Google Scholar

[9] K. Yatsunami, M. Ichida and S. Onodera: J Nat Med Vol. 62 (2008), p.63

Google Scholar

[10] C. Kuriyama, O. Kamiyama, K. Ikeda and F. Sanae: Bioorganic & Medicinal Chemistry Vol. 16 (2008), p.7330

Google Scholar

[11] M. Jamshid, N. PrakashR: Indian Journal of Pharmacology Vol. 40 (1)(2008),p.15

Google Scholar