Effect of Crystals Size, Surface Area and Pore Size of Hydroxyapatite Microspheres on the Loading Ability of Bovine Serum Albumin

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Effect of crystals size, surface area, pore size and porosity of hydroxyapatite microspheres on the loading ability of bovine serum albumin was studied in this paper. The surface morphology, specific surface area and porosity of hydroxyapatite microspheres were characterized by scanning electron microscope, specific surface area and pore size analyzer, respectively. The concentration of BSA in aqueous solutions both before and after adsorption was determined by ultraviolet-visible spectrophotometer. The results indicated that the adsorption behavior of bovine serum albumin appeared to obey the Langmuir-type isotherm model. Fast adsorption appeared at the beginning, and then decreased gradually. Hydroxyapatite microspheres calcined at 600°C had the maximum capacity, and those calcined at 800°C showed lower adsorption ability. The loading ability of hydroxyapatite microspheres depended on its crystal size, specific surface area, pore size and porosity, etc.

Info:

Periodical:

Advanced Materials Research (Volumes 197-198)

Edited by:

Huaiying Zhou, Tianlong Gu, Daoguo Yang, Zhengyi Jiang, Jianmin Zeng

Pages:

17-20

DOI:

10.4028/www.scientific.net/AMR.197-198.17

Citation:

J. M. Li et al., "Effect of Crystals Size, Surface Area and Pore Size of Hydroxyapatite Microspheres on the Loading Ability of Bovine Serum Albumin", Advanced Materials Research, Vols. 197-198, pp. 17-20, 2011

Online since:

February 2011

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Price:

$38.00

[1] M.B. Nair, S.S. Babu, H.K. Varma and A. Joh: Acta Biomaterialia Vol. 4 (2008), p.173.

[2] R.E. Riman, W.L. Suchanek, K. Byrappa, C.W. Chen, P. Shuk and C.S. Oakes: Solid State Ionics Vol. 151 (2002), p.393.

[3] F. Chen, Z.C. Wang and C.J. Lin: Materials Letters Vol. 57 (2002), p.858.

[4] Y. Boonsongrit, H. Abe, K. Sato, M. Naito, M. Yoshimura, H. Ichikawa and Y. Fukumori: Materials Science and Engineering B Vol. 148 (2008), p.162.

[5] S. Madhavi, C. Ferraris, T.J. White: J. Solid. State Chem. Vol. 178(2005) , p.2838.

[6] X. Chen, T. Wu, Q. Wang, J.W. Shen: Biomater Vol. 29(2008), p.2423.

[7] T.I. Ivanova, O.V. Frank-Kamenetskaya, A.B. Koltsov, V.L. Ugolkov: J. Solid. State Chem. Vol. 160(2001), p.340.

[8] H. Zhou, T. Wu, X. Dong, Q. Wang and J. Shen: Biochemical and Biophysical Research Communications Vol. 361 (2007), p.91.

[9] J.W. Shen, T. Wu, Q. Wang, H.H. Pan: Biomaterials Vol. 29 (2008) , p.513.

[10] H. Modarress, M. Mohsen-Nia: Journal of Biotechnology Vol. 131S (2007) , p. S254.

[11] M.T. Bernards, C. Qin and S. Jiang: Colloids and Surfaces B: Biointerfaces Vol. 64(2) (2008), p.236.

[12] S. Ouizat, A. Barroug1, A. Legrouri and C. Rey: Materials Research Bulletin, Vol. 34(1999), p.2279.

[13] K. Kandori, A. Fudo and T. Ishikawa: Colloids and Surfaces B: Biointerfaces Vol. 24 (2002), p.145.

[14] E.G. Ferrer, A. Bosch, O. Yantorno and E.J. Baran: Bioorganic & Medicinal Chemistry 16 (2008) 3878.

[15] L.Z. Wu, B.L. Ma, D.W. Zou, Z.X. Tie, J. Wang and W. Wang: Journal of Molecular Structure Vol. 877 (2008), p.44.

[16] R.E. Riman, W.L. Suchanek, K. Byrappa, C.W. Chen, P. Shuk and C.S. Oakes: Solid State Ionics Vol. 151 (2002), p.393.

[17] T. Kopac, K. Bozgeyik and J. Yener: Colloids and Surfaces. A Physicochemical and Engineering Aspects Vol. 322 (1-3) (2008), p.19.

[18] H. Krzysztof, M.B. Mirosław, B.M. Jadwiga, H. Maria, M. Włodzimierz, P. Tomasz, P. Anna and Z. Jerzy: J Eur Ceram Soc Vol. 26 (2006) , p.537.

[19] N. Patel, I.R. Glbson, S. Ke, S.M. Best and W. Bonfield: J Mater Sci: Mater Med Vol. 12(2001), pp.181-188.

[20] A.J. Wang, Y.P. Lu, R.F. Zhu, S.T. Li, G.Y. Xiao, G.F. Zhao and W.H. Xu: J Biomed Mater A Vol. 87 (2008), p.557.

[21] B. Wang, L.R. Teng, C.Y. Wang, Q.F. Meng, L.Z. Zhao and B. Gao: Chem Res Chin Vol. 23 (2007), p.254.

[22] K. Kawasaki, M. Kambara, H. Matsumura and W. Norde: Colloid Surf B Vol. 32(2003), p.321.

[23] W.K. Li and S.J. Li: Colloid Surf A Vol. 295(2007), p.159.

[24] K. Kontturi and M. Vuoristo: Desalination Vol. 104 (1996), p.99.

[25] T. Kopac, K. Bozgeyik and J. Yener: Colloid Surf A Vol. 322(2008), p.19.

[26] T. Matsumoto, M. Okazaki, M. Inoue, S. Yamaguchi, T. Kusunose, T. Toyonaga, Y. Hamada and J. Takahashi: Biomaterials Vol. 25(2004), p.3807.

DOI: 10.1016/j.biomaterials.2003.10.081

[27] O. Takagi, N. Kuramoto, M. Ozawa and S. Suzuki: Ceramics International Vol. 30 (2004), p.139.

[28] K. Kandori, A. Fudo and T. Ishikawa: Colloid Surf B Vol. 24(2002), p.145.

[29] T. Matsumoto, M. Okazaki, M. Inoue, S. Yamaguchi, T. Kusunose, T. Toyonaga, Y. Hamada and J. Takahashi: Biomaterials Vol. 25(2004), p.3807.

DOI: 10.1016/j.biomaterials.2003.10.081

[30] S. Ouizat, A. Barroug, A. Legrouri and C. Rey: Mater Res Bull Vol. 34(1999), p.2279.

[31] Information on http: /www. gsc. dicp. ac. cn/jxgl/fxzyk/6. ppt.

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