Effect of Crystals Size, Surface Area and Pore Size of Hydroxyapatite Microspheres on the Loading Ability of Bovine Serum Albumin

Abstract:

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Effect of crystals size, surface area, pore size and porosity of hydroxyapatite microspheres on the loading ability of bovine serum albumin was studied in this paper. The surface morphology, specific surface area and porosity of hydroxyapatite microspheres were characterized by scanning electron microscope, specific surface area and pore size analyzer, respectively. The concentration of BSA in aqueous solutions both before and after adsorption was determined by ultraviolet-visible spectrophotometer. The results indicated that the adsorption behavior of bovine serum albumin appeared to obey the Langmuir-type isotherm model. Fast adsorption appeared at the beginning, and then decreased gradually. Hydroxyapatite microspheres calcined at 600°C had the maximum capacity, and those calcined at 800°C showed lower adsorption ability. The loading ability of hydroxyapatite microspheres depended on its crystal size, specific surface area, pore size and porosity, etc.

Info:

Periodical:

Advanced Materials Research (Volumes 197-198)

Edited by:

Huaiying Zhou, Tianlong Gu, Daoguo Yang, Zhengyi Jiang, Jianmin Zeng

Pages:

17-20

DOI:

10.4028/www.scientific.net/AMR.197-198.17

Citation:

J. M. Li et al., "Effect of Crystals Size, Surface Area and Pore Size of Hydroxyapatite Microspheres on the Loading Ability of Bovine Serum Albumin", Advanced Materials Research, Vols. 197-198, pp. 17-20, 2011

Online since:

February 2011

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Price:

$35.00

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