Blood Compatibility of TiO2-xNx Thin Films Prepared by Improved Ultrasonic Spray Pyrolysis
Nitrogen-doped titanium oxide (TiO2-xNx) films were prepared by an improved ultrasonic spray pyrolysis device with buty1 titanate as the titanium source and ammonia as the nitrogen source. X-ray diffraction technique, scanning electronic microscope and UV-VIS spectroscopy were applied to study the microstructure, surface morphology and optical properties of the resulting films. The XRD peak intensity of the as-prepared films decreased with the increasing of nitrogen content and increased with the increasing of temperature, which indicates that the N doping introduced defects or strain in the TiO2 film. The SEM results indicate that all the samples have a nano-sized uniform surface. The smallest band gap and best hydrophobicity are obtained at the nitrogen concentration of 4 at. % and deposited at 400°C. The blood compatibility of TiO2-xNx thin films was observed through platelet adhesion. The experiments results show that the amount of thrombus on the TiO2-xNx thin films is much less than that of pyrolytic carbon. The experimental results show that the nano-sized TiO2-xNx thin films will be a new kind of promising materials applied to artificial heart valve and endovascula stent.
Huaiying Zhou, Tianlong Gu, Daoguo Yang, Zhengyi Jiang, Jianmin Zeng
X. S. Tang and D. Li, "Blood Compatibility of TiO2-xNx Thin Films Prepared by Improved Ultrasonic Spray Pyrolysis", Advanced Materials Research, Vols. 197-198, pp. 208-214, 2011