Blood Compatibility of TiO_2-xN_x Thin Films Prepared by Improved Ultrasonic Spray Pyrolysis

Abstract:

Nitrogen-doped titanium oxide (TiO_2-xN_x) films were prepared by an improved ultrasonic spray pyrolysis device with buty1 titanate as the titanium source and ammonia as the nitrogen source. X-ray diffraction technique, scanning electronic microscope and UV-VIS spectroscopy were applied to study the microstructure, surface morphology and optical properties of the resulting films. The XRD peak intensity of the as-prepared films decreased with the increasing of nitrogen content and increased with the increasing of temperature, which indicates that the N doping introduced defects or strain in the TiO₂ film. The SEM results indicate that all the samples have a nano-sized uniform surface. The smallest band gap and best hydrophobicity are obtained at the nitrogen concentration of 4 at. % and deposited at 400°C. The blood compatibility of TiO_2-xN_x thin films was observed through platelet adhesion. The experiments results show that the amount of thrombus on the TiO_2-xN_x thin films is much less than that of pyrolytic carbon. The experimental results show that the nano-sized TiO_2-xN_x thin films will be a new kind of promising materials applied to artificial heart valve and endovascula stent.

• Periodical: Advanced Materials Research (Volumes 197-198)
• Pages: 208-214
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.197-198.208
• Online since: February 2011
• Authors: Xiao Shan Tang, Da Li
• Keywords: Anticoagulant, Nitrogen Doping, TiO₂ Thin Films, Ultrasonic Spray Pyrolysis

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