Synthesis of O-Cation Chitosan
O-cationic Chitosan was prepared by self-made cationic ether agent 2,3-epoxypropyl trimethyl ammonium chloride(GTA) and chitosan. In this process, the effects of reaction solvent, reaction temperature, reaction time, amount of KOH and GTA on the substitution of O-cationic chitosan were studiedand the optimal reaction conditions were investigated. The optimal reaction conditions were as follows: reaction solvent Isopropanol, reaction time 30 h,reaction temperature 85 °C, KOH 3 mL（40 %） and the ratio of chitosan to GTA is 1:1.5.The degree of cationic is 55.36 %.
Zhong Cao, Lixian Sun, Xueqiang Cao, Yinghe He
F. L. Xing et al., "Synthesis of O-Cation Chitosan", Advanced Materials Research, Vols. 233-235, pp. 180-183, 2011