Effective Aerobic Oxidation of p-Nitrotoluene to p-nitrobenzoic acid Catalyzed by Manganese Dioxide and N-Hydroxyphthalimide
p-Nitrobenzoic acid could be efficiently prepared from aerobic oxidation of p-nitrotoluene using manganese dioxide (MnO2) and N-hydroxyphthalimide (NHPI) as catalysts. The conditions of oxidation were also optimaized: 97 % conversion of p-nitrotoluene and 89 % isolated yield of p-nitrobenzoic acid could be obtained at 110 °C under 0.4 MPa for 4 h in presence of 10 mol% NHPI and 10 mol% MnO2.
Zhong Cao, Lixian Sun, Xueqiang Cao, Yinghe He
W. Wang et al., "Effective Aerobic Oxidation of p-Nitrotoluene to p-nitrobenzoic acid Catalyzed by Manganese Dioxide and N-Hydroxyphthalimide", Advanced Materials Research, Vols. 233-235, pp. 317-320, 2011