Gold Magnetic Particle Based Immunoassay on a Disposable Microchips

Zi Ye Wang; Kang Wang; Xue Mei Ma

doi:10.4028/www.scientific.net/AMR.236-238.1931

Paper Titles

Study on Preparation, Biological Activity and Thermal Decomposition of N-Benzoyl-N＇-(4-Chlorobenzamido) Thiourea
p.1914

The Competitive Growth of BiOI and BiSI in the Solvothermal Process
p.1919

Investigation on Electronic Signals for Detection of Target DNA Molecule Based on Extended Gate FET Sensing Chip
p.1923

Formation and Magnetic Characterization of Magnesium Oxide / Iron Nano Composite Particles
p.1927

Gold Magnetic Particle Based Immunoassay on a Disposable Microchips
p.1931

Reduction of Supercooling of Water by TiO₂ Nanoparticles as Nucleating Agent
p.1935

Effects of Annealing on Microstructure and Mechanical Properties of Bulk Nanocrystalline Fe3Al Based Alloy with 10 Wt. % Mn Prepared by Aluminothermic Reaction
p.1939

Green Synthesis of Starch-Stabilized Silver Nanoparticles and their Antibacterial Properties
p.1945

Preparation of Biodegradable Gradient Polymer by Microwave
p.1949

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 236-238Gold Magnetic Particle Based Immunoassay on a...

Gold Magnetic Particle Based Immunoassay on a Disposable Microchips

Abstract:

Microchips appear to offer important opportunities for modern research. Microchips based on gold magnetic nanoparticles make manipulation of biomolecules more conveniently, and has the advantage of deducing reaction time. In this study, we first achieved microchips design and fabrication through CO₂ laser ablation for immunoassay, and then conjugated mouse IgG to gold magnetic nanoparticles serve as a target. Finally, HRP labeled goat anti mouse IgG binding assay and substrate reaction were performed with disposable microchips and other devices. The results indicated that the reactions carried on successfully and magnetic particles moved well in chips.