Synthesis, Crystal Structure and Antimicrobial Activity of a Mixed-Ligand Copper (II) Complex [Cu(pht)₂ (phen)H₂O]

Abstract:

A novel mixed-ligand copper(II) complex [Cu(pht)₂(phen)H₂O] (Hpht = 5,5-diphenylimidazolidine-2,4-dione, phen = 1,10-phenanthroline) was has been synthesized solvent-thermally and characterized by elemental analysis, IR and single-crystal X-ray diffraction. The crystal of the copper complex belongs to Triclinic system with space group P₁, a = 11.747(14), b = 12.639(15), c = 14.021(17)Å, α= 97.986(18)º, β= 104.958(18) º, γ= 108.485(19) º, V = 1851(4) ų, D_c = 1.371 g/cm³, Z = 2, F(000) = 790, µ = 0.644mm^-1, R₁ = 0.0835, wR₂ = 0.1436 [I>2σ(I)] and GOF＝0.867. The X-ray data showed that the Cu(II) atom adopted a distorted CuN₂O₃ square pyramidal configuration when coordinated with two phen ligands and one water ligand. The antimicrobial activity of the title complex was evaluated against a series of fungi or bacteria in vitro by agar method and the filter paper method, respectively．The results showed that the title complex was more active against the Fusarim gramine arum, Escherichia coli and Staphylococcus Aureus than its precursor Hpht and Cu(Ac)₂×H₂O.

• Periodical: Advanced Materials Research (Volumes 239-242)
• Pages: 2132-2136
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.239-242.2132
• Online since: May 2011
• Authors: Xi Lan Hu, Qin Jiang, Xing You Xu
• Keywords: Antimicrobial Activitiy, Complex, Copper(II), Crystal Structure

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