In view of the complexity in the design of serial parts of deck crane, by analyzing the structural characteristic of deck crane boom, this paper provides a similar design method for the serialization design of deck crane boom. A set of variant crane booms were expanded on the basis of the sample crane boom, the main parameters of which were extracted. CAE (computer aided engineering) simulations were performed to obtain FE models and structural responses of different crane booms in this series under standard working conditions. Stress distribution and deformation of different crane booms in the serial were analyzed. The FEA result implies that, the crane booms calculated from the sample with different design parameters still satisfy the structural strain requirement. Variation of stress value is consistent with academic calculation. This result also demonstrates the accuracy and feasibility of this serial design method.