Electrospraying or electrohydrodynamic spraying is a technique of liquid atomisation by utilising electrical forces. In the electrospraying technique, the liquid at the outlet of a nozzle is subjected to an electrical shear stress by maintaining the nozzle at high electric potential. This produces a fine mist of extremely small and in some cases down to nanometer size droplets. The charge and size of the droplets can be controlled by adjusting the flow rate and voltage applied to the nozzle. Extending the scope of electrospraying, textile substrates can be coated with suitable polymer solution to enhance the surface functionalisation. This paper highlights the deposition of chitosan on wool subtrates using elctrospraying and its potential application in medical textiles.