Progesterone Hydroxylation with Colletotrichum Lini AS3. 4486
The biotransformation of progesterone by Colletotrichum lini AS3. 4486 was studied. The formation of the product was monitored by HPLC. Product was purified from broth culture supernatants by silica gel column chromatography and identified as 7β,12β-dihydoxylprogesterone with MS, 1H NMR, 13C NMR and NOE.
Y. J. Shen et al., "Progesterone Hydroxylation with Colletotrichum Lini AS3. 4486", Advanced Materials Research, Vols. 343-344, pp. 1070-1073, 2012